Category: Database: Enzyme

Ribonuclease L (RNase L) 

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RNase L is an interferon-induced endoribonuclease that plays a key role in the mammalian innate immune response, particularly in antiviral…

Ribonuclease R (RNase R)

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Ribonuclease R (RNase R) is a 3′ to 5′ exoribonuclease that plays a crucial role in RNA metabolism, particularly in…

Telomerase

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Telomerase is a specialized ribonucleoprotein reverse transcriptase that plays a critical role in maintaining telomere length at the ends of…

DNA Polymerase β

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DNA Polymerase β (Pol β) is a DNA-dependent DNA polymerase primarily involved in base excision repair (BER) in eukaryotic cells….

DNA Polymerase III

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DNA Polymerase III is the primary enzyme responsible for chromosomal DNA replication in Escherichia coli and other prokaryotes. As a…

DNA Polymerase I

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DNA Polymerase I is a DNA-dependent DNA polymerase first discovered in Escherichia coli by Arthur Kornberg in 1956.  It was…

DNA-dependent DNA Polymerase

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DNA-dependent DNA polymerases are enzymes that catalyze the synthesis of a new DNA strand using an existing DNA template.  They…

Polymerase

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Polymerases are a fundamental class of enzymes responsible for synthesizing DNA and RNA molecules by forming phosphodiester bonds between nucleotides. …

Endoribonuclease

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Endoribonucleases are enzymes that catalyze the internal cleavage of RNA molecules by hydrolyzing the phosphodiester bonds within the RNA strand….

Ribonuclease T1 (RNase T1)

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Ribonuclease T1 (RNase T1) is a guanosine-specific endoribonuclease that cleaves single-stranded RNA at the 3′-end of guanine residues, generating RNA…

Ribonuclease H (RNase H)

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Ribonuclease H (RNase H) is an endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids, catalyzing the hydrolysis of…

Exonuclease III

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Exonuclease III (Exo III) is a bacterial 3′→5′ exonuclease derived from Escherichia coli, known for its ability to sequentially remove…

Ribonuclease A (RNase A)

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Ribonuclease A (RNase A) is a highly stable and well-characterized pancreatic endoribonuclease that specifically cleaves single-stranded RNA at the 3′-side…

Deoxyribonuclease I (DNase I)

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Deoxyribonuclease I (DNase I) is an endonuclease enzyme that catalyzes the cleavage of DNA by hydrolyzing the phosphodiester bonds between…

Reverse Transcriptase 

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Reverse transcriptase (RT) is an RNA-dependent DNA polymerase that catalyzes the synthesis of complementary DNA (cDNA) from an RNA template….