Category: Database: Gene/Protein

Hypoxia-Response Element

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Hypoxia-response elements (HREs) are short, cis-acting DNA sequences found within the promoter or enhancer regions of various genes that are…

Placental Growth Factor (PlGF)

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Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of signaling proteins, primarily known…

Neuropilin-1 (NRP-1)

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Neuropilin-1 (NRP-1) is a multifunctional, non-tyrosine kinase transmembrane glycoprotein that acts as a co-receptor for various signaling molecules.  It was…

Hypoxia-Inducible Factor-1 (HIF-1)

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Hypoxia-Inducible Factor-1 (HIF-1) is a transcription factor that plays a central role in cellular adaptation to low oxygen conditions (hypoxia). …

Vascular Permeability Factor

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Vascular Permeability Factor (VPF) is the original name given to what is now more commonly known as Vascular Endothelial Growth…

Vascular Endothelial Growth Factor-D (VEGF-D)

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Vascular Endothelial Growth Factor-D (VEGF-D) is a member of the VEGF family closely related to VEGF-C, and it primarily regulates…

Vascular Endothelial Growth Factor-C (VEGF-C)

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Vascular Endothelial Growth Factor-C (VEGF-C) is a member of the VEGF family best known for its central role in lymphangiogenesis,…

Vascular Endothelial Growth Factor-B (VEGF-B)

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Vascular Endothelial Growth Factor-B (VEGF-B) is a member of the VEGF family of signaling proteins, but unlike VEGF-A, it is…

Vascular Endothelial Growth Factor-A (VEGF-A)

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Vascular Endothelial Growth Factor-A (VEGF-A) is the most well-studied and biologically significant member of the VEGF family, recognized as the…

Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3)

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Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3, also known as Flt-4) is a receptor tyrosine kinase that plays a central role…

Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2)

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Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2, also called KDR in humans and Flk-1 in mice) is the principal mediator of…

Vascular Endothelial Growth Factor Receptor-1 (VEGFR-1)

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Vascular Endothelial Growth Factor Receptor-1 (VEGFR-1, also known as Flt-1) is one of the three main receptors in the VEGF…

Vascular Endothelial Growth Factor Receptor (VEGFR)

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Vascular endothelial growth factor receptors (VEGFRs) are a family of transmembrane receptor tyrosine kinases that mediate the effects of vascular…

Vascular Endothelial Growth Factor (VEGF)

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Vascular endothelial growth factor (VEGF) is a signaling protein that plays a central role in the formation of new blood…

TEX11

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TEX11 (Testis-Expressed Gene 11) is a gene located on the X chromosome that encodes a protein critically involved in meiotic…