Category: Database: Gene/Protein

AP-1 Transcription Factor

Loading

Activator Protein-1 (AP-1) is a collective term for a family of dimeric transcription factors that regulate gene expression in response…

JunB

Loading

JunB is a member of the Jun family of transcription factors, which includes c-Jun, JunB, and JunD.  Like its relatives,…

JunD

Loading

JunD is the third member of the Jun family of transcription factors, alongside c-Jun and JunB.  Like its relatives, JunD…

c-Jun

Loading

c-Jun is a transcription factor that belongs to the Jun family of proteins, which includes c-Jun, JunB, and JunD.  It…

Anthrax Toxin

Loading

The anthrax toxin is the primary virulence factor of Bacillus anthracis, responsible for much of the tissue damage, immune suppression,…

COP1 (Constitutive Photomorphogenic 1)

Loading

COP1 (Constitutive Photomorphogenic 1) is a highly conserved E3 ubiquitin ligase that plays pivotal roles in both plants and animals…

Ubiquitin

Loading

Ubiquitin is a small, highly conserved protein found in virtually all eukaryotic cells.  It is only 76 amino acids long…

ZBED6

Loading

ZBED6 (Zinc Finger BED-Type Containing 6) is a transcriptional regulator unique to placental mammals.  It is unusual in origin because…

Von Willebrand Factor (vWF)

Loading

Von Willebrand factor (vWF) is a large multimeric glycoprotein that plays a central role in hemostasis, the process that stops…

AMPA Receptor

Loading

The AMPA receptor (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) is a subtype of ionotropic glutamate receptor that mediates fast excitatory synaptic transmission in…

DNA Methyltransferase

Loading

DNA methyltransferases (DNMTs) are a family of enzymes responsible for catalyzing the transfer of a methyl group to DNA, primarily…

Histone Acetyltransferase

Loading

Histone acetyltransferases (HATs) are enzymes that catalyze the transfer of acetyl groups from acetyl-CoA to the ε-amino group of lysine…

CCCTC-Binding Factor (CTCF)

Loading

CCCTC-binding factor (CTCF) is a highly conserved and multifunctional DNA-binding protein that plays a central role in the organization of…

Alpha-synuclein

Loading

Alpha-synuclein is a small, soluble, intrinsically disordered protein composed of 140 amino acids and predominantly expressed in the central nervous…

Histone H4

Loading

Histone H4 is one of the four core histone proteins—along with H2A, H2B, and H3—that form the fundamental unit of…