Category: Lab Notes: Cell Biology

Ectopic Expression

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Ectopic expression refers to the abnormal or unintended activation of a gene in a cell type, tissue, or developmental stage…

Cellular Homeostasis

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Cellular homeostasis refers to the maintenance of a stable internal environment within cells despite changes in external conditions. This dynamic…

Motor Proteins

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Motor proteins are molecular machines that convert chemical energy from ATP into mechanical work, enabling essential cellular processes like vesicle…

Cell Migration

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Cell migration is a fundamental biological process where cells move from one location to another. This complex process is essential…

Lamellipodia

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Lamellipodia are thin, sheet-like membrane protrusions at the leading edge of migrating cells. These dynamic structures play a crucial role…

Chemotaxis

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Chemotaxis is the directed movement of cells in response to chemical gradients. This fundamental process enables cells to move toward…

Signal Transduction

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Signal transduction refers to the process by which cells convert external signals into internal responses. This complex system allows cells…

Transcriptional Regulation in Epithelial-to-Mesenchymal Transition (EMT)

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Transcriptional regulation is a central mechanism in controlling epithelial-to-mesenchymal transition (EMT), orchestrating the complex gene expression changes that allow epithelial…

Snail Transcription Factor in Epithelial-to-Mesenchymal Transition (EMT)

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Snail is a critical transcription factor involved in the process of Epithelial-to-Mesenchymal Transition (EMT), which is essential for various physiological…

Fibronectin in Epithelial-to-Mesenchymal Transition (EMT)

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Fibronectin is a large, extracellular matrix (ECM) glycoprotein that plays a central role in epithelial-to-mesenchymal transition (EMT) by facilitating cell-matrix…

N-cadherin in Epithelial-to-Mesenchymal Transition (EMT) 

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N-cadherin, a type of cadherin that mediates calcium-dependent cell-cell adhesion, plays a crucial role in epithelial-to-mesenchymal transition (EMT) by facilitating…

Vimentin in Epithelial-to-Mesenchymal Transition (EMT)

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Vimentin is a type III intermediate filament protein that plays a pivotal role in the structural reorganization and phenotypic transformation…

E-cadherin in Epithelial-to-Mesenchymal Transition (EMT)

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E-cadherin, or epithelial cadherin, is a transmembrane glycoprotein that plays a fundamental role in maintaining the structure and integrity of…

Matrix Metalloproteinase-3 (MMP-3) in Epithelial-to-Mesenchymal transition (EMT)

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Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, plays an important role in the induction and progression of epithelial-to-mesenchymal transition (EMT),…

Exocytosis

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Exocytosis is a cellular process where materials are transported out of the cell via membrane-bound vesicles that fuse with the…