Category: Database: Antibiotics

Methicillin

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Methicillin is a semi-synthetic β-lactam antibiotic that was developed in the late 1950s as part of the penicillin class of…

Leptomycin B

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Leptomycin B (LMB) is a potent antifungal antibiotic first isolated from Streptomyces bacteria. It is a specific inhibitor of nuclear…

Amphotericin B Toxicity

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Amphotericin B, a polyene antifungal agent, has long been considered the gold standard for treating serious systemic fungal infections. Despite…

Reducing Amphotericin B Toxicity

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Amphotericin B stands as one of the most effective broad-spectrum antifungal agents in modern medicine, maintaining its significance despite being…

Amphotericin B Lozenges

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Amphotericin B lozenges represent a specialized pharmaceutical formulation designed specifically for the management of oral fungal infections. These medicated lozenges…

Amphotericin B Colloidal Dispersion

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Amphotericin B colloidal dispersion (ABCD) represents a significant advancement in antifungal therapy, specifically designed to overcome the limitations of conventional…

Kanamycin B

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Kanamycin B represents a significant variant in the kanamycin family of aminoglycoside antibiotics, distinguished by its unique structural characteristics and…

Kanamycin C

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Kanamycin C is another member of the kanamycin aminoglycoside family, differentiated by its unique structural characteristics and specific antimicrobial properties….

Kanamycin A

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Kanamycin A stands as a significant member of the aminoglycoside family of antibiotics, first discovered in the soil bacterium Streptomyces…

ChemDB: Kanamycin Sulfate

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Chemical Name: Kanamycin monosulfate (a mixture of kanamycin A, B, and C sulfates) Molecular Formula: Kanamycin A: C₁₈H₃₆N₄O₁₁·H₂SO₄ Kanamycin B:…

Gentamicin

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Gentamicin is one of the most widely used aminoglycoside antibiotics, particularly valued for its effectiveness against gram-negative bacterial infections. First…

Aminoglycosides

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Aminoglycosides are potent broad-spectrum antibiotics primarily effective against aerobic gram-negative bacteria. These drugs were first discovered with streptomycin in 1943,…

Minocycline

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Minocycline is a second-generation tetracycline antibiotic that has become a valuable tool in modern medicine due to its versatility and…

Tetracyclines

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Tetracyclines are a class of broad-spectrum antibiotics that have been extensively used in clinical medicine and scientific research since their…

Aminocoumarins

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Aminocoumarins are a class of antibiotics that target bacterial DNA topoisomerases, specifically DNA gyrase and topoisomerase IV. These enzymes are…