Category: Database: Gene/Protein

The VBC complex—composed of von Hippel–Lindau protein (pVHL), elongin B, and elongin C—is a multiprotein assembly that plays a pivotal…

RING-box protein 1 (Rbx1) (RING-box protein 1), also known as ROC1 or RBX1, is a small but essential protein that…

Cullin-2 (CUL2) is a member of the cullin family of scaffold proteins that form the structural backbone of Cullin–RING ubiquitin…

Elongin C is a small adaptor protein that functions as a core component of several multiprotein complexes involved in transcriptional…

Elongin B is a small, ubiquitously expressed protein that functions as a regulatory and adaptor subunit in multiple multiprotein complexes. …

Hypoxia-inducible factor alpha (HIF-α) is the oxygen-sensitive subunit of the hypoxia-inducible factor (HIF) transcriptional complex, which serves as the master…

Elongin A is a transcription elongation factor that plays a key role in enhancing the rate and efficiency of RNA…

Placental growth factor-2 (PlGF-2) is a splice variant of placental growth factor (PlGF), a member of the vascular endothelial growth…

Placental growth factor-1 (PlGF-1) is one of the major isoforms of placental growth factor (PlGF), a member of the vascular…

Semaphorin 3A (Sema3A) is a secreted glycoprotein that belongs to the class 3 semaphorins, a family of signaling molecules originally…

Prolyl hydroxylase domain protein 3 (PHD3), also known as EGLN3, is one of the three main isoforms of the prolyl…

Prolyl hydroxylase domain protein 2 (PHD2), also known as EGLN1, is the most critical and widely expressed isoform of the…

Prolyl hydroxylase domain protein 1 (PHD1), also known as EGLN2 (Egl-9 homolog 2), is one of the three major isoforms…

Prolyl hydroxylase domain proteins (PHDs), also known as EGLNs (Egl-9 homologs), are a family of oxygen-, iron-, and 2-oxoglutarate–dependent dioxygenases…

The von Hippel–Lindau protein (pVHL) is a tumor suppressor protein encoded by the VHL gene located on chromosome 3p25–26.  It…