Category: Database: Gene/Protein
Histone H3
Histone H3 stands as one of the most fundamental and highly conserved proteins in eukaryotic organisms, playing a central role…
Histone H2A
Histone H2A represents one of the core histone proteins that play a fundamental role in chromatin organization and regulation within…
Histone H2B
Histone H2B is one of the core histone proteins that play a fundamental role in chromatin organization and regulation of…
Caspase-4
Caspase-4 is an inflammatory caspase primarily involved in the innate immune response and inflammatory cell death (pyroptosis). Unlike executioner caspases,…
Caspase-1
Caspase-1, also known as interleukin-1β converting enzyme (ICE), is a critical inflammatory caspase that plays a central role in innate…
Caspase-3
Caspase-3 is a crucial executioner caspase that plays a central role in the implementation phase of apoptosis. As one of…
Caspase-10
Caspase-10 is a member of the cysteine-aspartic acid protease (caspase) family that plays a crucial role in the initiation of…
Caspase-8
Caspase-8 is a crucial initiator caspase that plays a central role in the extrinsic apoptotic pathway and serves as a…
Caspase-2
Caspase-2 is one of the most evolutionarily conserved members of the caspase family and possesses unique characteristics that set it…
Caspase
Caspases (Cysteine-dependent aspartate-directed proteases) are a family of enzymes that play crucial roles in programmed cell death (apoptosis) and inflammation….
BAK1 (BCL2 Antagonist/Killer 1)
BAK1 (BCL2 Antagonist/Killer 1) is a pro-apoptotic member of the BCL-2 protein family that plays a crucial role in programmed…
BAX (Bcl-2-Associated X Protein)
BAX (Bcl-2-associated X protein) is a pro-apoptotic member of the BCL-2 protein family that plays a central role in programmed…
Regulation of SHP-2 by Calpeptin
SHP-2 (Src homology region 2 domain-containing phosphatase-2) is a non-receptor protein tyrosine phosphatase encoded by the PTPN11 gene. It plays…
Calpeptin
Calpeptin is a cell-permeable synthetic peptide inhibitor that specifically targets calpains, which are calcium-dependent cysteine proteases. This compound has become…
BCL2 (B-cell Lymphoma 2)
BCL2 (B-cell lymphoma 2) is a critical regulator of programmed cell death (apoptosis) and serves as the founding member of…