Category: Lab Notes: Genetics
Chromatin Remodeling
Chromatin remodeling is a dynamic process by which the structure of chromatin—the complex of DNA and histone proteins in the…
Genome Biology
Genome biology is the broad and interdisciplinary study of the structure, function, evolution, and regulation of genomes—the complete set of…
Genomic Medicine
Genomic medicine is an emerging field of healthcare that harnesses knowledge of the human genome to improve the diagnosis, treatment,…
Herring
Herring are small, oily fish belonging to the family Clupeidae, widely recognized for their ecological and economic importance. There are…
Non-Coding DNA
Non-coding DNA refers to the vast regions of the genome that do not encode proteins. While the human genome comprises…
Single-Nucleotide Polymorphism (SNP)
A single-nucleotide polymorphism (SNP) is the most common type of genetic variation among individuals, involving a change at a single…
Relationship Between Genetic Variation and Phenotypic Variation
The relationship between genetic variation and phenotypic variation lies at the heart of genetics, evolutionary biology, and personalized medicine. Genetic…
Genome-Wide Association Study (GWAS)
A Genome-Wide Association Study (GWAS) is a powerful research approach used to identify genetic variants across the entire genome that…
Nucleosome
The nucleosome is the fundamental structural unit of chromatin in eukaryotic cells. It plays a critical role in organizing the…
Histone Code
The histone code is a fundamental concept in epigenetics that describes how specific chemical modifications to histone proteins regulate gene…
Chromosome
Chromosomes are highly organized structures composed of DNA and proteins that carry genetic information within living organisms. These remarkable molecular…
Ectopic Expression Vs Heterologous Expression
Criteria Ectopic Expression Heterologous Expression Remarks Definition Expression of a gene in a different tissue, cell type, or subcellular location…
Ectopic Expression
Ectopic expression refers to the abnormal or unintended activation of a gene in a cell type, tissue, or developmental stage…
Mutant
In genetics, a mutant is any organism, cell, or virus that has undergone a mutation—a change in its DNA sequence…
Isogenic Mutant
Isogenic mutants are genetically engineered organisms or cell lines that are identical to their parental (wild-type) counterparts in every aspect…