Category: Database: Gene/Protein
Promyelocytic Leukemia Protein
Promyelocytic Leukemia (PML) protein is a tumor suppressor protein that plays crucial roles in various cellular processes and is primarily…
14-3-3 Protein
14-3-3 proteins are a family of highly conserved regulatory molecules found in all eukaryotic cells, from yeast to humans. These…
TRIB1
TRIB1 (Tribbles Pseudokinase 1) is a member of the Tribbles family of pseudokinases that plays crucial roles in various cellular…
Pseudokinase
Pseudokinases are protein domains that share significant structural similarity with protein kinases but lack key catalytic residues required for phosphoryl…
ETS Transcription Factor Family
The ETS (E26 Transformation-Specific) family of transcription factors represents one of the largest families of signal-dependent transcriptional regulators in metazoans,…
MEK1/2
MEK1/2 (also known as MAP2K1/2 or MAPK/ERK kinase 1/2) are dual-specificity protein kinases that play a central role in the…
MEKK1
MEKK1 (MAP3K1, Mitogen-activated protein kinase kinase kinase 1) is a serine/threonine protein kinase that functions as a critical upstream regulator…
RBX2
RBX2 (RING-box protein 2), also known as ROC2 or SAG (Sensitive to Apoptosis Gene), is a RING finger protein that…
CUL4B
CUL4B (Cullin 4B) is a member of the cullin family of proteins that serves as a scaffold component of CRL4B…
CUL4A
CUL4A (Cullin 4A) is a crucial scaffold protein that forms part of the CRL4 (Cullin-RING ligase 4) E3 ubiquitin ligase…
FBW7
FBW7 (F-box and WD repeat domain-containing 7), also known as FBXW7, is a critical tumor suppressor protein that functions as…
Translocated Promoter Region (TPR)
The Translocated Promoter Region (TPR) protein is a large, complex nuclear pore complex (NPC) component that plays essential roles in…
FOXO1
FOXO1 (Forkhead Box O1) is a crucial transcription factor belonging to the FOXO family of proteins, which plays fundamental roles…
MG132
MG132 (carbobenzoxy-Leu-Leu-leucinal) is a synthetic peptide aldehyde that functions as a potent, reversible, and cell-permeable inhibitor of the proteasome. It…
Proteasome
The proteasome is a large, multi-subunit protease complex responsible for the regulated degradation of intracellular proteins. It is a central…