Category: Lab Notes

Anchorage independent growth refers to the ability of a cell to grow and proliferate in absence of ECM-integrin interaction. Such…

Please read the following references. REFERENCES Karginov & Hannon, 2010. The CRISPR system: small RNA-guided defense in bacteria and archaea….

Synonyms Ficoll 400, Polysucrose-400, Ficoll PM 400q CAS Number 26873-85-8 Chemical structure (C12H20O10)n Molecular Weight ≈ 400,000 Appearance White to…

Preparing the gel casting tray by sealing both edges (open ends) with tape for agarose gel preparation requires effort. Sometimes agarose solution leaks especially when relatively hot melton agarose is poured into the gel casting tray. To make the agarose gel casting process simple and effortless, many suppliers provide casting tray setups that do not need sealing the edges of casting trays. Some of them are listed in this post.

IUPAC name 3-morpholin-4-yl propane-1-sulfonic acid Synonym 4-Morpholinepropanesulfonic acid3-(N-Morpholino)propanesulfonic acid3-Morpholinopropanesulfonic acidMorpholinopropanesulfonic acid4-Morpholinopropanesulphonic acid4-Morpholinepropane sulfonic acid3-N-Morpholinopropanesulfonic acid Molecular formula C7H15NO4S Molecular weight…

OVERVIEW MOPS is a zwitterionic physiological buffer, with pH range 6.5 – 7.9. MOPS-containing  electrophoresis buffer is suitable for RNA…

Integrins are reported to regulate the following cellular functions. Cell survival and death Cell cycle progression and proliferation Cell shape…

α1 integrin subunit  α2 integrin subunit  α3 integrin subunit  α4 integrin subunit  α5 integrin subunit  α6 integrin subunit  α7 integrin…

α1β1 integrin  α2β1 integrin  α3β1 integrin  α4β1 integrin  α5β1 integrin  α6β1 integrin  α7β1 integrin  α8β1 integrin  α9β1 integrin  α10β1 integrin …

Aberrant integrin signaling is reported in the following diseases Thrombosis  Autoimmune diseases  Cancer

Integrins play pivotal roles in the following physiological processes Wound repair Immunity Hemostasis

List of integrin ligands Bone sialoprotein (BSP) Collagen (extracellular matrix proteins) Cysteine rich protein 61 (CCN1) Developmental locus-1 (Del-1) Elastin…

The International System of Units (SI) defines 7 base units as standard units of measurement. They are listed in the…

The density of water is dependent on temperature. The maximum density of pure water is 1 g/mL (more precisely 0.999973…