Is DMSO Safe?

• DMSO is a widely used solvent in laboratories, as well as in industrial and medical applications. 
• While it’s generally safe when used properly, its ability to penetrate biological membranes and transport dissolved substances into the bloodstream poses significant risks. This characteristic necessitates specific protective measures, including the use of appropriate glove materials like butyl rubber or neoprene, rather than standard nitrile or latex gloves, which provide inadequate protection.
• Its hygroscopic nature requires careful storage conditions, and its potential to react violently with strong oxidizing agents and acid chlorides demands attention to chemical compatibility. When heated, DMSO can generate hazardous decomposition products, particularly sulfur oxides, making proper ventilation crucial. 
• The most commonly reported impacts of DMSO on human health include a characteristic garlic-like breath odor and body odor, which occurs because the compound is metabolized to dimethyl sulfide. When applied topically, it can cause skin reactions such as redness, burning, itching, and irritation. More serious impacts can include severe allergic reactions, headaches, changes in blood pressure, respiratory issues, and severe skin reactions. DMSO may also interact with certain medications, potentially altering their effectiveness or increasing side effects.
• Laboratory personnel must strictly follow institutional safety guidelines, standard operating procedures (SOPs), and Material Safety Data Sheets (MSDS) when handling DMSO. Before use, carefully review the MSDS to understand potential hazards and required precautions. 
• Proper personal protective equipment (PPE), including butyl rubber or neoprene gloves, eye protection, and lab coats, must be worn, as nitrile and latex gloves provide inadequate protection. All manipulations should be performed in a chemical fume hood to minimize vapor exposure.

Note: The information presented here is for informational purposes only and should not be considered a substitute for professional medical advice. Always consult a healthcare provider for personalized guidance and recommendations.
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