Category: Database: Gene/Protein

Note: For more detailed and accurate information, please read the cited reference. Overexpressed Pragmin is localized to cytoplasm in the…

Note: For more detailed and accurate information, please read the cited reference. Pragmin overexpression induces morphological changes in AGS cells,…

Note: For more detailed and accurate information, please read the cited reference. Pragmin overexpression causes morphological changes in AGS cell…

Note: For more detailed and accurate information, please read the cited reference. Overexpression of Pragmin in the AGS cell line…

Synonym:  Pragmin SgK223 Subcellular localization: Cytoplasm Pseudokinase Contain EPIYA-moitif Tyrosine phosphorylation at the EPIYA motif by SFKs (Safari et al.,…

Express relatively high level of p53 and p21 Undergo senescence (early passage cells) Post-mitotic tetraploid cell-cycle arrest and polyploidy Aberrant…

Embryonic lethal, die between E11.5 and E12.5 (Grisendi et al., 2005)

qPCR primers for Mouse β-Actin Source: Li et al., 2008. supplementary information Forward Primer: 5’-GCTGTGCTATGTTGCTCTAG-3’ Reverse Primer:  5’-CGCTCGTTGCCAATAGTG-3’ #

qPCR primers for Mouse GAS1 Source: Li et al., 2008. supplementary information Forward Primer: 5’-TCCCCTTACCGATTCATTCCT-3’ Reverse Primer:  5’-CAATCGCCAGCTCCACACT-3’ #

CDK4 primers for Mouse Nucleolin Source: Li et al., 2008. supplementary information Forward Primer: 5’-GCAGTCTACATACGCAACAC-3’ Reverse Primer:  5’-TCGTCTTCTGGAGGCAATC-3’ #

qPCR primers for Mouse Nucleolin Source: Li et al., 2008. supplementary information Forward Primer: 5′-ACACCAGCCAAAGTCATTCC-3′ Reverse Primer:  5′-ATCCTCATCACTGTCTTCCTTC-3′ #

NPM is important for the oncogenic functions of c-Myc. Its overexpression enhances the hyperproliferation and transformation driven by c-Myc, while…

Nucleophosmin (NPM) plays a significant role in cell transformation, particularly through its interaction with c-Myc. In their 2008 study, Li…

Note: The protein nucleophosmin is commonly referred to as NPM or NPM1 in the literature. Nucleophosmin can enhance cell proliferation. …

Note: The protein nucleophosmin is commonly referred to as NPM or NPM1 in the literature. The protein Nucleophosmin is primarily…