Category: Lab Notes: Biotechniques
Structured Illumination Microscopy
Structured illumination microscopy (SIM) is a powerful super-resolution imaging technique that enhances spatial resolution beyond the diffraction limit of conventional…
Microscopy
Microscopy is a foundational technique in science that allows for the observation of structures too small to be seen with…
Light-Sheet Fluorescence Microscopy (LSFM)
Light-sheet fluorescence microscopy (LSFM), also known as selective plane illumination microscopy (SPIM), is an advanced imaging technique that allows rapid,…
Optical Sectioning
Optical sectioning is a microscopy technique that enables the capture of thin, focused slices (or “sections”) of a specimen along…
Microscope
Microscopes are essential scientific instruments that extend the human ability to observe objects and structures far smaller than what the…
Differential Interference Contrast (DIC) Microscopy Vs Phase Contrast Microscopy
Criteria Differential Interference Contrast (DIC) Microscopy Phase Contrast Microscopy Remarks Principle Converts phase shifts in light passing through a specimen…
Fluorescence Microscope
A Fluorescence Microscope is a specialized optical microscope that uses fluorescence and phosphorescence to study properties of organic and inorganic…
Light Microscope
A Light Microscope, also known as an optical microscope, is a fundamental scientific instrument that uses visible light and a…
Scanning Electron Microscope
A Scanning Electron Microscope (SEM) is a sophisticated imaging device that creates detailed three-dimensional-appearing images of specimen surfaces by scanning…
Transmission Electron Microscope
The Transmission Electron Microscope (TEM) represents one of the most powerful tools in scientific imaging, capable of achieving atomic-level resolution…
Dissecting Microscope
A dissecting microscope, also known as a stereomicroscope, is a versatile optical instrument designed for observing specimens at relatively low…
Confocal Microscope
A confocal microscope represents a sophisticated advancement in optical imaging technology, providing researchers with the ability to capture high-resolution, three-dimensional…
Electron Microscope
An electron microscope is a sophisticated scientific instrument that uses beams of electrons instead of light to create images of…
Inverted Microscope
An inverted microscope is a specialized form of light microscope where the light source and condenser are positioned above the…
Visium Spatial Gene Expression
Visium Spatial Gene Expression, developed by 10x Genomics, is a powerful spatial transcriptomics platform that enables researchers to analyze gene…