Category: Lab Notes

Growth factor/mitogenic signaling is required for G1 phase progress. Withdrawal of growth factors/mitogens from cell culture can arrest the cells…

The G1 phase begins with the generation of daughter cells following cytokinesis and ends when daughter cells are ready to…

Constitutive expression of cyclin A and E can overcome pRb-mediated suppression of proliferation (Hinds et al., 1992). REFERENCES Hinds et…

The following kinases can phosphorylate Rb Cyclin D-CDK4  Cyclin D-CDK6 Cyclin E-CDK2  Stress-activated protein kinases of the p38 family

Cell Cycle Cell Cycle Phases Interphase (Cell Cycle) Antephase (Cell cycle) Cyclin B1 Subcellular Localization During Cell Cycle List of…

In some situations, proliferating cells stop cell division and exit the cell cycle in the G1 phase. These nonproliferative cells…

During cell division, dividing cells enter a complex and highly regulated series of events, the cell cycle, that result in…

A typical mammalian cell cycle can have the following distinct phases: G1 phase S phase G2 phase M phase: Generation…

The first stage of mitosis Early stages of chromosome condensation in prophase are reversible in many organisms. The initiation of…

During the G2 phase, cyclin B1 is localized in the cytoplasm. Cyclin B1 accumulation on centrosome start in the mid-G2…

Cyclin B1 is the main B-type cyclin, which regulates cell cycle progression during the transition from interphase to mitosis as…

Both Cyclin A and Cyclin B are considered mitotic cyclins. Both cyclins are synthesized and degraded around the same time…

NPAT (also known as p220) (Histone modification) HIRA (Histone modification) CBP/p300 (Histone modification) Cdt1 (DNA replication) BRCA1 (DNA repair) Ku70…

Karayiannis et al., 2023. Induction of MMP-3 and MMP-9 expression during Helicobacter pylori infection via MAPK signaling pathways. Helicobacter. 28(4),…

pRb (An upstream regulator of cyclin A) E2F1 (Transcription factor) B-Myb (Transcription factor) Cdc6 (DNA replication) HSSB (Also known as…