Category: Database: Gene/Protein
Nucleophosmin (NPM)
Synonyms: Nucleophosmin/B23 Nucleophosmin Numatrin B23 NPM NPM1 NO38 Note: NPM1 is commonly referred to as nucleophosmin, while other nucleophosmins like…
ORC1
Large subunit of Origin Recognition Complex (ORC) Play role in initiation of replication of genomic DNA In humans, ORC1 is…
Argonaute (AGO)
Highly conserved Discovered in a screen aimed to identify new genes involved in Arabidopsis thaliana development Play central role in…
Interaction of Rab11FIP4 with ARF5
We found only one research article that suggests an interaction of Rab11FIP4 with ARF5. The interaction of Rab11FIP4 with ARF5…
CagA associates with c-Met, E-cadherin, and p120-catenin in a multiproteic complex that suppresses Helicobacter pylori-induced cell-invasive phenotype.
Oliveira et al., 2009. CagA associates with c-Met, E-cadherin, and p120-catenin in a multiproteic complex that suppresses Helicobacter pylori-induced cell-invasive…
CagA (Cytotoxin-Associated Gene A)
CagA (Cytotoxin-Associated Gene A) is a protein encoded by the cagA gene, which is found in specific strains of Helicobacter…
StudyTools: Calpain Cleavage–resistant Mutant of Integrin β3 Subunit
Calpain cleavage–resistant mutant of integrin β3 subunit is generated by replacing Arginine at position 760 (located in the cytoplasmic domain…
ExpSup: CagA Induces P21 Expression
Murata-Kamiya et al., 2007 showed that cagA expression in MKN-28 cell line results in upregulation of p21WAF1/Cip1 using western blotting….
ExpSup: CagA Induces Cyclin D1 Expression
Murata-Kamiya et al., 2007 showed that cagA expression in MKN-28 cell line results in upregulation of cyclin D1 using western…
ExpSup: CagA Induces β-catenin Relocalization from Cell Membrane to Nucleus in Tyrosine-phosphorylation Independent Manner
Murata-Kamiya et al., 2007 showed that β-catenin is localized in the plasma membrane at cell-cell junctions in the MKN-28 cell…
ExpSup: CagA Activates β-catenin in Tyrosine-phosphorylation Independent Manner
β-catenin is usually present in the plasma membrane at cell-cell junctions in a complex called adherens junction. Upon activation, β-catenin…
ExpSup: CagA Physically Interacts with E-cadherin in Tyrosine-phosphorylation Independent Manner
Murata-Kamiya et al., 2007 showed that E-cadherin physically interacts with CagA protein using co-immunoprecipitation in cell lysate prepared from MKN-28…
CagA/E-cadherin interaction
CagA physically interacts with E-cadherin and this interaction is independent of CagA tyrosine phosphorylation status (Murata-Kamiya et al., 2007). …
ExpSup: Hummingbird Phenotype is Induced only by CagA-positive Helicobacter pylori, but not by CagA-negative Helicobacter pylori
AGS cells acquire hummingbird phenotype when infected with CagA-positive H. pylori strain G27 but not with CagA-negative H. pylori strain…