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Bactericidal Antibiotics Vs Bacteriostatic Antibiotics
Criteria Bactericidal Antibiotics Bacteriostatic Antibiotics Remarks Definition Kill bacteria directly by targeting vital processes Inhibit bacterial growth and reproduction without…
Antibiotics: Timeline of Key Events
Pre-20th Century Ancient Times: Use of moldy bread and plant extracts in Egypt, Greece, and China to treat infections—primitive antibacterial…
Antibiotic Resistance Mechanisms in Bacteria
Antibiotic resistance is a growing global health threat that compromises the effective treatment of bacterial infections. Bacteria have evolved various…
Antibiotics Crossing the Blood-Brain Barrier
Antibiotics that can cross the blood-brain barrier (BBB) are critical for treating infections of the central nervous system (CNS), such…
ChemDB: Minocycline
Chemical Name:*(4S,4aR,5aR,12aS)-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide* Molecular Formula: C₂₃H₂₇N₃O₇ Molecular Weight: 457.49 g/mol Appearance: Yellow crystalline powder (hydrochloride salt is more water-soluble) Solubility: Water:…
Minocycline
Minocycline is a second-generation tetracycline antibiotic that has become a valuable tool in modern medicine due to its versatility and…
Tetracycline Derivatives and Novel Drug Development
Tetracycline antibiotics, originally developed in the mid-20th century, have evolved significantly beyond their initial use as broad-spectrum antimicrobials. Structural modifications…
Neuroprotective Effects of Minocycline
Minocycline, a second-generation tetracycline antibiotic, has gained significant attention in recent years for its neuroprotective properties, which extend well beyond…
Tetracyclines in Cancer Therapy
Tetracyclines, traditionally known for their role as broad-spectrum antibiotics, have gained attention for their non-antibiotic properties, including anticancer activity. Among…
Tetracyclines in Autoimmune Diseases
Tetracyclines, long known for their antimicrobial properties, have emerged as promising therapeutic agents in the management of several autoimmune diseases. …
ChemDB: Tetracycline Hydrochloride
Chemical name: (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride Molecular formula: C₂₂H₂₄N₂O₈·HCl Appearance: Bright yellow crystalline powder Solubility: Water: 10–12 mg/mL (pH 2–4) DMSO: ~50…
Mitochondrial Protein Synthesis Vs Cytoplasmic Protein Synthesis (Animal Cell)
Criteria Mitochondrial Protein Synthesis Cytoplasmic Protein Synthesis (Animal Cells) Remarks Location Occurs in the mitochondrial matrix Occurs in the cytoplasm…
Mitochondrial Ribosome Vs Cytoplasmic Ribosome (Animal Cell)
Criteria Mitochondrial Ribosome (Mitoribosome) Cytoplasmic Ribosome (Animal Cell) Remarks Location Located within the mitochondrial matrix Found in the cytoplasm and…
Tetracyclines
Tetracyclines are a class of broad-spectrum antibiotics that have been extensively used in clinical medicine and scientific research since their…
Impact of Doxycycline on Cell Proliferation and Metabolism
Doxycycline is widely used in molecular biology and biomedical research, particularly as a regulator in inducible gene expression systems such…