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Caspase-4
Caspase-4 is an inflammatory caspase primarily involved in the innate immune response and inflammatory cell death (pyroptosis). Unlike executioner caspases,…
Caspase-1
Caspase-1, also known as interleukin-1β converting enzyme (ICE), is a critical inflammatory caspase that plays a central role in innate…
Caspase-3
Caspase-3 is a crucial executioner caspase that plays a central role in the implementation phase of apoptosis. As one of…
Caspase-10
Caspase-10 is a member of the cysteine-aspartic acid protease (caspase) family that plays a crucial role in the initiation of…
Caspase-9
Caspase-9 is a crucial initiator caspase that plays a central role in the intrinsic (mitochondrial) apoptotic pathway. It serves as…
Caspase-8
Caspase-8 is a crucial initiator caspase that plays a central role in the extrinsic apoptotic pathway and serves as a…
Caspase-2
Caspase-2 is one of the most evolutionarily conserved members of the caspase family and possesses unique characteristics that set it…
Caspase
Caspases (Cysteine-dependent aspartate-directed proteases) are a family of enzymes that play crucial roles in programmed cell death (apoptosis) and inflammation….
BAK1 (BCL2 Antagonist/Killer 1)
BAK1 (BCL2 Antagonist/Killer 1) is a pro-apoptotic member of the BCL-2 protein family that plays a crucial role in programmed…
BAX (Bcl-2-Associated X Protein)
BAX (Bcl-2-associated X protein) is a pro-apoptotic member of the BCL-2 protein family that plays a central role in programmed…
Helicobacter pylori Lineage Comparison: hpAfrica1, hpAfrica2, hpNEAfrica, hpEurope, hpAsia2, hpSahul, hpEastAsia
Criteria hpAfrica1 hpAfrica2 hpNEAfrica hpEurope hpAsia2 hpSahul hpEastAsia Remarks Geographic Origin Central and West Africa Southern Africa Northeastern Africa (e.g.,…
Helicobacter pylori hpAfrica1 Vs hpAfrica2 Vs hpNEAfrica
Criteria hpAfrica1 hpAfrica2 hpNEAfrica Remarks Geographic Origin West and Central Africa Southern Africa Northeastern Africa (Horn of Africa, Egypt, Sudan)…
Regulation of SHP-2 by Calpeptin
SHP-2 (Src homology region 2 domain-containing phosphatase-2) is a non-receptor protein tyrosine phosphatase encoded by the PTPN11 gene. It plays…
Calpeptin
Calpeptin is a cell-permeable synthetic peptide inhibitor that specifically targets calpains, which are calcium-dependent cysteine proteases. This compound has become…
BCL2 (B-cell Lymphoma 2)
BCL2 (B-cell lymphoma 2) is a critical regulator of programmed cell death (apoptosis) and serves as the founding member of…