Author: admin
Coumermycin
Coumermycin is a member of the aminocoumarin class of antibiotics, characterized by its potent activity against bacterial DNA gyrase, a…
Polyclonal Antibodies Vs Monoclonal Antibodies
Criteria Polyclonal Antibodies Monoclonal Antibodies Remarks Definition A heterogeneous mixture of antibodies produced by multiple B-cell clones Homogeneous antibodies derived…
Phagocytosis
Phagocytosis is a fundamental cellular process where specialized cells engulf and destroy particles, pathogens, and dead cells. This process is…
Antigen
An antigen is any substance that can trigger an immune response and be specifically recognized by the immune system. These…
Innate Immunity Vs Adaptive Immunity
Criteria Innate Immunity Adaptive Immunity Remarks Definition First line of defense with non-specific response Second line of defense with antigen-specific…
Hypersensitivity
Hypersensitivity refers to exaggerated or inappropriate immune responses that cause tissue damage and disease, rather than protection. Unlike normal immune…
Adaptive Immunity
Adaptive immunity is a highly specific defense system that develops throughout our lifetime in response to exposure to pathogens and…
Innate Immunity
Innate immunity represents the body’s first line of defense against pathogens, consisting of both physical barriers and cellular responses that…
Whole Exome Sequencing (WES)
Whole Exome Sequencing (WES) is a powerful genomic technique that focuses on sequencing all protein-coding regions (exons) of genes in…
CagA – PAR1b/MARK2 Interaction
The Helicobacter pylori CagA protein is a multifunctional effector injected into host gastric epithelial cells via the type IV secretion…
Topic: SHP-2 (Src Homology Region 2-containing Protein Tyrosine Phosphatase-2)
SHP-2 (Src Homology Region 2-containing Protein Tyrosine Phosphatase-2) Tissue Expression of SHP-2 Subcellular Localization of SHP-2 Ref: Epigenetic regulation and…
Tissue Expression of SHP-2
SHP-2 (PTPN11) is a widely expressed protein tyrosine phosphatase that plays crucial roles in various cellular processes throughout the body….
Subcellular Localization of SHP-2
SHP-2 is primarily a cytoplasmic protein but exhibits dynamic subcellular localization depending on signaling events. It contains two SH2 domains…
How Targeting CagA can Interrupt Helicobacter pylori Pathogenesis
CagA (Cytotoxin-associated gene A) is a key virulence factor that transforms H. pylori from a simple colonizer into a highly…
Strategies to Target CagA: A Multifaceted Approach to Combat Helicobacter pylori Pathogenesis
Helicobacter pylori (H. pylori) is a Gram-negative, microaerophilic bacterium that colonizes the human gastric mucosa and is associated with a…