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Matrix Metalloproteinase-3 (MMP-3) in Epithelial-to-Mesenchymal transition (EMT)
Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, plays an important role in the induction and progression of epithelial-to-mesenchymal transition (EMT),…
Exocytosis
Exocytosis is a cellular process where materials are transported out of the cell via membrane-bound vesicles that fuse with the…
Membrane Recycling
Membrane recycling is a crucial cellular process that involves the continuous internalization, sorting, and reuse of membrane components and associated…
Vesicle Trafficking
Vesicle trafficking is a fundamental cellular process that orchestrates the organized movement of membrane-bound compartments within cells, enabling the transport…
Endocytosis
Endocytosis is a fundamental cellular process through which cells internalize substances from their external environment by forming membrane-bound vesicles. This…
Topic: Epithelial-to-Mesenchymal Transition (EMT)
Epithelial-to-Mesenchymal Transition (EMT) Key Indicators for Monitoring Epithelial-to-Mesenchymal Transition (EMT) Tools for Studying Epithelial-to-Mesenchymal Transition (EMT) Matrix Metalloproteinase-3 (MMP-3) in…
Key Indicators for Monitoring Epithelial-to-Mesenchymal Transition (EMT)
Feature Epithelial Mesenchymal Remarks Morphology Cobblestone-like Spindle-shaped, motile Morphological shift is often the first visible sign of EMT. E-cadherin High…
Tools for Studying Epithelial-to-Mesenchymal Transition (EMT)
Epithelial-to-mesenchymal transition (EMT) can be studied through a multidisciplinary approach that integrates morphological assessment, gene expression analysis, and functional assays,…
Helicobacter pylori CagA protein induces factors involved in the epithelial to mesenchymal transition (EMT) in infected gastric epithelial cells in an EPIYA- phosphorylation-dependent manner.
Sougleri et al., 2016. Helicobacter pylori CagA protein induces factors involved in the epithelial to mesenchymal transition (EMT) in infected…
Mesenchymal Stem Cell (MSC) Markers
Mesenchymal stem cells (MSCs) are multipotent stromal cells capable of differentiating into various cell types, including osteoblasts, adipocytes, and chondrocytes. …
Mesenchymal Markers
Mesenchymal markers are proteins commonly expressed by mesenchymal cells — cells that are typically spindle-shaped, motile, and found in connective…
Translocation-deficient cagE Knockout Strain of Helicobacter pylori
A translocation-deficient cagE knockout strain of Helicobacter pylori is a genetically modified variant in which the cagE gene—an essential component…
Matrix metalloproteinase-3 (MMP-3)
Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a member of the matrix metalloproteinase family—enzymes responsible for the degradation and…
Epithelial Polarity
Epithelial polarity refers to the distinct distribution of cellular structures and functions within epithelial cells, which line surfaces and cavities…