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Ref: Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer.
Koh et al., 2018. Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer. Cell Biosci. 8, 50….
Ref: Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites.
Higashi et al., 2002. Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine…
Ref: Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells.
Kim et al., 2018. Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells….
SHP-1 (Src Homology Region 2-containing Protein Tyrosine Phosphatase-1)
SHP-1 (Src homology region 2-containing protein tyrosine phosphatase-1), encoded by the PTPN6 gene, is a cytoplasmic protein tyrosine phosphatase predominantly…
SHP-2 (Src Homology Region 2-containing Protein Tyrosine Phosphatase-2)
SHP-2 (Src homology region 2-containing protein tyrosine phosphatase-2), encoded by the PTPN11 gene, is a widely expressed protein tyrosine phosphatase…
Hepatocyte Growth Factor (HGF)
Hepatocyte Growth Factor (HGF), also known as scatter factor, is a multifunctional cytokine that plays crucial roles in cell proliferation,…
ExpSup: CagA Undergoes Tyrosine Phosphorylation in Non-Gastric COS-7 Cells
Background: CagA undergoes tyrosine phosphorylation in gastric epithelial cell lines, such as the AGS cell line. Interestingly, it has also…
ExpSup: Membrane Localization of CagA is Independent of Tyrosine Phosphorylation
The following experimental approaches support the notion that “Membrane localization of CagA is independent of tyrosine phosphorylation”. Immunofluorescence analysis of…
Ref: SHP-2 Tyrosine Phosphatase as an Intracellular Target of Helicobacter pylori CagA Protein.
Higashi et al., 2002. SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science. 295(5555), 683-686. PMID-11743164;…
Mucosal-Associated Lymphoid Tissue (MALT)
Mucosal-associated lymphoid tissue (MALT) is a specialized component of the immune system located at mucosal surfaces throughout the body. These…
Gastric Diseases
Gastric diseases encompass a wide range of disorders that affect the stomach, impairing its ability to perform essential digestive and…
Helicobacter pylori: Infection Patterns and Trends
Across the globe, Helicobacter pylori infection weaves a complex and uneven pattern. Today, it is estimated that more than half…
Epidemiology
Epidemiology is the study of how diseases and other health-related conditions are distributed in populations, and the factors that influence…
Glossary
Glossary Glossary: 0-9  λDE3 Lysogen Glossary: A  araBAD Promoter lossary: B Glossary: C  Chemotaxis  Casein Zymography  Caseinolytic activity Caseinolytic Proteases …
Cellular Homeostasis
Cellular homeostasis refers to the maintenance of a stable internal environment within cells despite changes in external conditions. This dynamic…