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Discovery of the Transforming Principle: Frederick Griffith’s Pioneering Work
Frederick Griffith’s 1928 experiments were a landmark study in biology, demonstrating the phenomenon of bacterial transformation. His work laid crucial…
Boveri-Sutton Chromosome Theory of Inheritance
The Boveri–Sutton chromosome theory states that chromosomes are the carriers of genetic material and play a crucial role in heredity. …
Topic: Cytotoxin-Associated Gene A (CagA)
CagA (Cytotoxin-Associated Gene A) CagA Types Based on EPIYA Motifs EPIYA Motifs CagA – PAR1b/MARK2 Interaction CagA/E-cadherin interaction Phosphorylation-Independent CagA…
ExpSup: Pragmin Is Localized to the Cytoplasm
Note: For more detailed and accurate information, please read the cited reference. Overexpressed Pragmin is localized to cytoplasm in the…
ExpSup: Pragmin Tyrosine Phosphorylation at EPIYA Motif is Required for Morphological Changes in AGS Cells
Note: For more detailed and accurate information, please read the cited reference. Pragmin overexpression induces morphological changes in AGS cells,…
ExpSup: Pragmin Overexpression Induces Morphological Changes in AGS Cell Line
Note: For more detailed and accurate information, please read the cited reference. Pragmin overexpression causes morphological changes in AGS cell…
ExpSup: Pragmin Induces c-Src Activation
Note: For more detailed and accurate information, please read the cited reference. Overexpression of Pragmin in the AGS cell line…
pCMV-Script Vector
Vector type: Mammalian expression plasmid vector Based on: high-copy-number pUC plasmid vector Bacterial system: Selection: Kanamycin (Kanamycin-resistance gene under control…
Pragmin
Synonym: Pragmin SgK223 Subcellular localization: Cytoplasm Pseudokinase Contain EPIYA-moitif Tyrosine phosphorylation at the EPIYA motif by SFKs (Safari et al.,…
NPM -/- Mouse Embryonic Fibroblasts
Express relatively high level of p53 and p21 Undergo senescence (early passage cells) Post-mitotic tetraploid cell-cycle arrest and polyploidy Aberrant…
qPCR Primers for β-Actin
qPCR primers for Mouse β-Actin Source: Li et al., 2008. supplementary information Forward Primer: 5’-GCTGTGCTATGTTGCTCTAG-3’ Reverse Primer: 5’-CGCTCGTTGCCAATAGTG-3’ #
qPCR Primers for ELF1a
qPCR primers for Mouse ELF1a Source: Li et al., 2008. supplementary information Forward Primer: 5’-AAAATTGGCTACAACCCCGA-3’ Reverse Primer: 5’-CCAACCAGAAATTGGCACAA-3’ #
qPCR Primers for Mouse GAS1
qPCR primers for Mouse GAS1 Source: Li et al., 2008. supplementary information Forward Primer: 5’-TCCCCTTACCGATTCATTCCT-3’ Reverse Primer: 5’-CAATCGCCAGCTCCACACT-3’ #
qPCR Primers for EIF4E
qPCR primers for Mouse EIF4E Source: Li et al., 2008. supplementary information Forward Primer: 5’-GGACGGGATTGAGCCTATGTG-3’ Reverse Primer: 5’-CAGCAGTGTCTCTAGCCAGAAG-3’ #