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ChemDB: SP600125
Chemical Name SP600125 Synonym SP 600125, 1,9-Pyrazoloanthrone, Anthrapyrazolone Molecular formula C14H8N2O Molecular Weight 220.23 CAS Number 129-56-6 Color Yellow Solubility…
Suppliers: PD98059
Note: PD98059 can be purchased from the following suppliers. You must visit the supplier’s product page to order and to…
SP600125
Overview: An anthrapyrazolone Selective inhibitor of JNKs (Bennett et al., 2001) Reversible ATP- competitive inhibitor Often used to understand the…
Suppliers: SP600125
Note: SP600125 can be purchased from the following suppliers. You must visit the supplier’s product page to order and to…
List of Common Substrates of CDK1-Cyclin A and CDK2-Cyclin A
CDK1-cyclin A and CDK2-cyclin A share several substrates. MCMs (DNA replication) Cdc7 (DNA replication) Ribonucleotide reductase R2 (DNA replication) pRb …
List of Mammalian APC/C Substrates
Anillin Aurora kinase A Aurora kinase B Cyclin A2 Cyclin B1 Cell division cycle-associated protein 3 (Also known as Tome-1) …
List of Cell Cycle Regulators Knockout Mice
Cyclin D1-/-: Viable, Reduced body size, Neurological abnormalities, Hypoplastic retinas Cyclin D2-/-: Viable, defects in B-cell proliferation, pancreatic beta cell…
List of G1-phase Regulators
Cyclin D family member Cyclin D1 Rb family members pRb/p105: pRb/p105 associates with the E2F activators and prevents them from…
List of Mitosis Regulators
Cyclin B1: Cyclin B1 interacts with CDK1 in late G2 and in M-phase and controls entry and progression through the…
List of Spindle Assembly Checkpoint (SAC) Regulators
INCENP (Inner centrosome protein) Aurora B Survivin Borealin Cdc20 BubR1 Bub3 Mad2 Emi1
List of CDK1 Substrates
Actopaxin Adenomatous polyposis coli Amphiphysin1 BARD1 BRCA2 Caldesmon Cdc7 Cdc20 Cdc25A Cdc25 C Cdh1 Cdk7 C/EBPβ CKII Dynein Dystrophin EF-1…
List of CDK2 Substrates
BARD1 B-Myb BRCA1 BRCA2 CBP/p300 Cdc6 Cdc7 Cdk7 Cdt1 C/EBPβ DP1 hHR6A HIRA Ku70 Marcks MCM2 MCM4 MyoD NPAT Npm…