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Dicer
Dicer is a highly conserved, multidomain enzyme that plays a fundamental role in RNA interference (RNAi) and microRNA (miRNA) processing…
Double-Stranded RNA
Double-stranded RNA (dsRNA) is a molecular structure in which two complementary RNA strands are bound together by Watson–Crick base pairing,…
Adenosine Deaminase
Adenosine deaminase (ADA) is a crucial metabolic enzyme that plays a vital role in purine metabolism and immune system function….
Adenosine-to-Inosine (A-to-I) RNA Editing
Adenosine-to-inosine (A-to-I) RNA editing is one of the most widespread and well-studied forms of post-transcriptional RNA modification in metazoans. It…
Translocated Promoter Region (TPR)
The Translocated Promoter Region (TPR) protein is a large, complex nuclear pore complex (NPC) component that plays essential roles in…
FOXO1
FOXO1 (Forkhead Box O1) is a crucial transcription factor belonging to the FOXO family of proteins, which plays fundamental roles…
MG132
MG132 (carbobenzoxy-Leu-Leu-leucinal) is a synthetic peptide aldehyde that functions as a potent, reversible, and cell-permeable inhibitor of the proteasome. It…
Proteasome
The proteasome is a large, multi-subunit protease complex responsible for the regulated degradation of intracellular proteins. It is a central…
AP-1 Transcription Factor
Activator Protein-1 (AP-1) is a collective term for a family of dimeric transcription factors that regulate gene expression in response…
JunB
JunB is a member of the Jun family of transcription factors, which includes c-Jun, JunB, and JunD. Like its relatives,…
JunD
JunD is the third member of the Jun family of transcription factors, alongside c-Jun and JunB. Like its relatives, JunD…
c-Jun
c-Jun is a transcription factor that belongs to the Jun family of proteins, which includes c-Jun, JunB, and JunD. It…
Autosomal Recessive Disorder
Autosomal recessive disorders occur when an individual inherits two copies of a mutated gene, one from each parent. These conditions…
Autosomal Dominant Disorder
Autosomal dominant disorders are genetic conditions that can occur when an individual inherits just one copy of a mutated gene…
Anthrax Toxin
The anthrax toxin is the primary virulence factor of Bacillus anthracis, responsible for much of the tissue damage, immune suppression,…