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Placental growth factor-2 (PlGF-2) is a splice variant of placental growth factor (PlGF), a member of the vascular endothelial growth…

Placental growth factor-1 (PlGF-1) is one of the major isoforms of placental growth factor (PlGF), a member of the vascular…

Semaphorin 3A (Sema3A) is a secreted glycoprotein that belongs to the class 3 semaphorins, a family of signaling molecules originally…

Prolyl hydroxylase domain protein 3 (PHD3), also known as EGLN3, is one of the three main isoforms of the prolyl…

Prolyl hydroxylase domain protein 2 (PHD2), also known as EGLN1, is the most critical and widely expressed isoform of the…

Prolyl hydroxylase domain protein 1 (PHD1), also known as EGLN2 (Egl-9 homolog 2), is one of the three major isoforms…

Prolyl hydroxylase domain proteins (PHDs), also known as EGLNs (Egl-9 homologs), are a family of oxygen-, iron-, and 2-oxoglutarate–dependent dioxygenases…

The von Hippel–Lindau protein (pVHL) is a tumor suppressor protein encoded by the VHL gene located on chromosome 3p25–26.  It…

Hypoxia-response elements (HREs) are short, cis-acting DNA sequences found within the promoter or enhancer regions of various genes that are…

Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of signaling proteins, primarily known…

Neuropilin-1 (NRP-1) is a multifunctional, non-tyrosine kinase transmembrane glycoprotein that acts as a co-receptor for various signaling molecules.  It was…

Hypoxia-Inducible Factor-1 (HIF-1) is a transcription factor that plays a central role in cellular adaptation to low oxygen conditions (hypoxia). …

Vascular Permeability Factor (VPF) is the original name given to what is now more commonly known as Vascular Endothelial Growth…

Vascular Endothelial Growth Factor-D (VEGF-D) is a member of the VEGF family closely related to VEGF-C, and it primarily regulates…

Vascular Endothelial Growth Factor-C (VEGF-C) is a member of the VEGF family best known for its central role in lymphangiogenesis,…