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Capillary Electrophoresis

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Capillary electrophoresis (CE) is a powerful analytical technique used to separate ionic species based on their size-to-charge ratio. It is…

Automation of Sanger Sequencing Using Fluorescent Dideoxynucleotides and Capillary Electrophoresis

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Sanger sequencing, developed by Frederick Sanger in the late 1970s, was the first widely adopted method for determining the nucleotide…

DNA Sequencer

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A DNA sequencer is a laboratory instrument used to determine the precise order of nucleotides—adenine (A), thymine (T), cytosine (C),…

Bacteriophage ϕX174

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Bacteriophage ϕX174 is a well-studied virus that infects Escherichia coli and related bacteria. It belongs to the family Microviridae and…

DNA Sequencing: Timeline of Key Events

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DNA sequencing, the process of determining the precise order of nucleotides in a DNA molecule, has revolutionized biology, biotechnology, and…

Shotgun Sequencing

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Shotgun sequencing is a powerful and widely used approach to DNA sequencing that involves randomly breaking a genome into numerous…

Maxam–Gilbert Sequencing

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Maxam–Gilbert sequencing, also known as chemical sequencing, is one of the first DNA sequencing methods ever developed. Introduced in 1977…

First-Generation Sequencing

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First-Generation Sequencing encompasses the earliest set of DNA sequencing technologies developed in the 1970s and 1980s, which provided the first…

Third-Generation Sequencing (TGS)

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Third-Generation Sequencing (TGS) refers to a set of advanced DNA sequencing technologies that enable the direct reading of long DNA…

Topic: Sequencing

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Sanger Sequencing   DNA Sequencing High-Throughput Genomic Sequencing Technology RNA-sequencing (RNA-seq) Next-Generation Sequencing (NGS)   Illumina Sequencing by Synthesis Whole Exome…

DNA Origami

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DNA origami is a nanoscale engineering technique that uses the predictable base-pairing rules of DNA to fold a long single-stranded…

DNA-Based Tools

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DNA-based tools have transformed the landscape of biotechnology, offering unprecedented precision, scalability, and versatility across fields such as medicine, agriculture,…

DNA Digital Data Storage

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DNA digital data storage is an emerging technology that uses the molecular structure of DNA to encode, store, and retrieve…

DETECTR (DNA Endonuclease Targeted CRISPR Trans Reporter)

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DETECTR (DNA Endonuclease Targeted CRISPR Trans Reporter) is a CRISPR-based molecular diagnostic platform designed for the sensitive and specific detection…

SHERLOCK (Specific High-sensitivity Enzymatic Reporter unLOCKing)

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SHERLOCK (Specific High-sensitivity Enzymatic Reporter unLOCKing) is a nucleic acid detection platform that leverages the collateral cleavage activity of CRISPR-associated…