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GBM39

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Human patient-derived glioma xenolines (Watkins et al., 2014) REFERENCES: Watkins et al., 2014. Disruption of astrocyte-vascular coupling and the blood-brain…

Blood-Brain Barrier (BBB)

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The BBB is a highly specialized structure in the Central nervous system (CNS) between the blood circulation and the brain…

Protocol – Growing Large Volume of Liquid Culture of Escherichia coli for Large-Scale Plasmid Isolation

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Large-scale isolation of plasmid requires a large volume of E. coli culture. Large scale plasmid isolation procedures are termed, midiprep (25 – 50 ml starting culture volume) and maxiprep (100 – 500 ml starting culture volume). A starter culture is initially prepared by inoculating a colony in a small volume (2 – 10 ml) of culture medium. Large culture volume is prepared by diluting starter culture in a ratio of 1: 100 to 1: 1000 in the growth medium.

GBM22

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Human patient-derived glioma xenolines (Watkins et al., 2014) REFERENCES: Watkins et al., 2014. Disruption of astrocyte-vascular coupling and the blood-brain…

Cell Line : D54MG

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Human glioma cell line (Watkins et al., 2014) REFERENCES: Watkins et al., 2014. Disruption of astrocyte-vascular coupling and the blood-brain…

D54MG Glioma Cell Line-Derived Brain Tumors in Immunodeficient Mice

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Transplantation of 1.25 – 5.0 x 105 cells in the brain of adult 6 – 12 weeks old  immunodeficient C.B.17…

Interaction of Glioma Cells with Pre-existing Blood Vessels (Vessel Co-option)

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The interaction of glioma cells with blood vessels has a high impact on glioma development, therefore has been considered as…

Glioma Cell Lines that Show Extensive Perivascular Invasion in Rodent Brain

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The following cell lines have been shown to invade perivascularly when transplanted into the rodent brain. D54 (Watkins et al.,…

Preparation of Lambda-agar medium and plates

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Lambda-agar is nothing but a lambda broth which is solidified by agar. Agar is a solidifying agent. It melts at 85°C but melton agar stays liquid at a temperature > 40°C (this property is called hysteresis, different temperatures for melting and solidifying). This allows us to add heat-labile medium supplements such as antibiotics and vitamins and prepare solid medium. Lambda-agar solid medium is prepared by dissolving 15 g agar / liter of Lambda broth.

Preparation of TNT Medium

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OVERVIEW TNT medium is a moderately rich medium. It contains tryptone, sodium chloride (NaCl) and thiamine. Tryptone provides basic nutrients…

Methods for Detecting Antibiotic-resistant Bacteria

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Please read the following peer-reviewed articles to know different methods to detection of antibiotic-resistant bacteria: Ash et al., 2002.  Antibiotic…

Preparation of Superbroth

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Overview Superbroth contains very high-levels of Tryptone and yeast extract that makes it a super rich medium. It can be…