Category: Lab Notes
Glutamyl Endopeptidase
Glutamyl endopeptidase (also known as glutamyl-specific protease or V8 protease) is a serine endopeptidase that specifically hydrolyzes peptide bonds on…
Carboxypeptidase A
Carboxypeptidase A (CPA) is a crucial digestive enzyme that plays a specialized role in protein metabolism. As a zinc-dependent exopeptidase,…
Carboxypeptidase B
Carboxypeptidase B (CPB) represents a specialized class of digestive enzyme that plays a pivotal role in protein metabolism. As a…
SupEvidence: CagA Induces EMT-Like Changes in AGS Cells
Helicobacter pylori is a gastric pathogen closely associated with the development of gastric cancer. One of its major virulence factors,…
Stromelysin-1
Stromelysin-1, also known as Matrix Metalloproteinase-3 (MMP-3), is an enzyme belonging to the matrix metalloproteinase family. These enzymes play a…
Whole Exome Sequencing (WES)
Whole Exome Sequencing (WES) is a powerful genomic technique that focuses on sequencing all protein-coding regions (exons) of genes in…
CagA – PAR1b/MARK2 Interaction
The Helicobacter pylori CagA protein is a multifunctional effector injected into host gastric epithelial cells via the type IV secretion…
Topic: SHP-2 (Src Homology Region 2-containing Protein Tyrosine Phosphatase-2)
SHP-2 (Src Homology Region 2-containing Protein Tyrosine Phosphatase-2) Tissue Expression of SHP-2 Subcellular Localization of SHP-2 Ref: Epigenetic regulation and…
Tissue Expression of SHP-2
SHP-2 (PTPN11) is a widely expressed protein tyrosine phosphatase that plays crucial roles in various cellular processes throughout the body….
Strategies to Target CagA: A Multifaceted Approach to Combat Helicobacter pylori Pathogenesis
Helicobacter pylori (H. pylori) is a Gram-negative, microaerophilic bacterium that colonizes the human gastric mucosa and is associated with a…