Category: Lab Notes
SHP-1 Expression in AGS Cell Line
SHP-1 expression in the AGS cell line appears to be minimal under normal conditions (Higashi et al., 2002, Kim et…
Ref: Epigenetic regulation and anti-tumorigenic effects of SH2-containing protein tyrosine phosphatase 1 (SHP1) in human gastric cancer cells.
Joo et al., 2016. Epigenetic regulation and anti-tumorigenic effects of SH2-containing protein tyrosine phosphatase 1 (SHP1) in human gastric cancer…
Ref: Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer.
Koh et al., 2018. Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer. Cell Biosci. 8, 50….
Ref: Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites.
Higashi et al., 2002. Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine…
Ref: Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells.
Kim et al., 2018. Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells….
ExpSup: CagA Undergoes Tyrosine Phosphorylation in Non-Gastric COS-7 Cells
Background: CagA undergoes tyrosine phosphorylation in gastric epithelial cell lines, such as the AGS cell line. Interestingly, it has also…
ExpSup: Membrane Localization of CagA is Independent of Tyrosine Phosphorylation
The following experimental approaches support the notion that “Membrane localization of CagA is independent of tyrosine phosphorylation”. Immunofluorescence analysis of…