Category: Lab Notes

List of CDK5 Substrates

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Amphiphysin1 Cables Disabled1 Doublecortin Munc18 Nudel p53 Pctaire1 Protein phosphatase inhibitor 1 PSD-95 Stat3 mSds3 SynapsinI Tyrosine hydroxylase

List of CDK7 Substrates

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CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 p53 RARγ RNA pol II

Rab11FIP4 in Hepatocellular carcinoma (HCC)

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Upregulation of Rab11FIP4 has been reported in Hepatocellular carcinoma tissues and cell lines Expression of Rab11FIP4 correlates with a worse/poor…

Rab11FIP4 (Rab11-Family Interacting Protein 4)

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Protein name Rab11FIP4 (Rab11-family interacting protein 4) Synonyms Rab11-FIP4, Rab11FIP4, Rab11-family interacting protein 4 Functions Intracellular vesicle trafficking and recyclingTransport…

Cell Counting Kit-8 (CCK-8)

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Purpose Relative measurement of cell viability and proliferation of tissue culture cells Detection method Colorimetric Assay format (Platform) Multiwell plate…

Suppliers: Cell Counting Kit-8 (CCK-8)

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Note: Cell Counting Kit-8 (CCK-8) can be purchased from the following suppliers. You must visit the supplier’s product page to…

​​List of CDK1-Cyclin B Substrates

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Histones (Chromosome condensation) HMG-1 (Chromosome condensation) RIIα (Chromosome condensation) Nir2 (Fragmentation of the Golgi network) p47 (Fragmentation of the Golgi…

List of Yeast APC/C Substrates

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IPL1  CLB2  CDC6  CDC20  MIH1  CDC8  CDH1/HCT1  CDC5  PDS1  SGO1  UBC11

CDK1-Cyclin B1 Complex

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The Cdk1-cyclin B1 kinase triggers mitosis in most eukaryotes.   The complex between Cdk1-cyclin B1 functions as a kinase (serine-threonine kinase)…

Anaphase

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Anaphase refers to a phase in mitosis. In anaphase, the central spindle microtubules start to bundle and position the actomyosin…

Anaphase-Promoting Complex/Cyclosome (APC/C)

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The Anaphase-promoting complex/cyclosome (APC/C) is a large multi-subunit E3 ubiquitin ligase that plays a crucial role in cell cycle regulation….

Cytokinesis

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Cytokinesis is the last phase of the cell cycle that results in the generation of daughter cells. Cytokinesis is precisely…

Mitogenic Signaling in Cell Cycle Progression

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Mitogenic signaling is required for cells to enter the cell cycle. In the absence of mitogenic signaling, cells stop division…

Mammalian Cell Cycle Progression

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A typical cell division results in the generation of two identical daughter cells. Soon after formation, daughter cells either enter…