Category: Lab Notes

Diseases caused by Helicobacter pylori

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Helicobacter pylori infection has been shown to be highly associated with the following diseases: Gastritis Peptic ulcer Duodenal ulcer Gastric…

Kanamycin

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Kanamycin is a broad-spectrum aminoglycoside antibiotic effective against a wide range of gram-negative bacteria, including Escherichia coli, Klebsiella pneumoniae, Proteus…

Escherichia coli K-12

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The majority of laboratory strains of E. coli are derived from E. coli K-12 Favorite model organism to study bacterial…

Escherichia coli DH5α

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One of the most common laboratory Escherichia coli strains used for molecular cloning Derived from Escherichia coli K-12 High transformation…

Calculator – Calculate Molarity of Concentrated Sodium Hydroxide (NaOH) (w/w)

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Calculator – Calculate molarity of concentrated Sodium Hydroxide (NaOH) Use Calculator to calculate the molarity of concentrated Sodium Hydroxide (NaOH)…

Topic: Calcium Chloride (CaCl2)

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Preparation of 1M Calcium chloride (CaCl2) Stock Solution Calcium Chloride (CaCl2) Molecular Weight Calculation Calcium Chloride Dihydrate (CaCl2.2H2O) Molecular Weight…

Pichia pastoris

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A methylotrophic yeast  Discovered in 1960, with the unique ability to utilize methanol as a carbon source and energy A…

Methylotrophs

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A diverse group of microorganisms that can utilize single carbon (C1) compounds such as methane, methanol, and methylamine, as a…

Methanol Metabolism by Methylotrophs

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The first step of methanol metabolism is the oxidation of methanol which leads to the formation of  formaldehyde Formaldehyde is…

Yeast in Biotechnology

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Has a long history in biotechnology Safe for humans as it has long been used for Beer production Tools are…

Saccharomyces cerevisiae

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Classification Kingdom Fungi Division Ascomycota Subdivision Saccharomycotina Class Saccharomycetes Orders Saccharomycetales Family Saccharomycetaceae Genus Saccharomyces Species cerevisiae Common names: baker’s…

How to Calculate the Molecular Weight of a Compound?

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To calculate the molecular weight of any compound, the first step is to know the constituent elements (atoms) and their…

Chloramphenicol Amplification of Low-copy Number Plasmids

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Low-copy number plasmid vectors such as those based on pMB1 or ColE1 can be amplified by adding chloramphenicol to the…

Plasmid: pBR322 (Cloning Vector)

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Plasmid name pBR322 Application Cloning vector Replicon pMBI Host E. coli DH5α, and other related strains Plasmid size (kbp) 4.361…

Plasmid Isolation: Genomic DNA vs Plasmid DNA

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One of the major challenges in plasmid isolation methods is the separation of plasmid DNA from genomic DNA. To better…