Category: Lab Notes
Trimethoprim
Trimethoprim is a diaminopyrimidine antibiotic with a molecular formula of C14H18N4O3 and a molecular mass of 290.32 g/mol. Its structure…
Ciprofloxacin
Ciprofloxacin is a second-generation fluoroquinolone antibiotic with a molecular formula of C17H18FN3O3 and a molecular mass of 331.34 g/mol. Its…
Chloramphenicol
Chloramphenicol is a broad-spectrum antibiotic with a molecular formula of C11H12Cl2N2O5 and a molecular mass of 323.13 g/mol. Its structure…
Cefoxitin
Cefoxitin is a second-generation cephalosporin antibiotic with a molecular formula of C16H17N3O7S2 and a molecular mass of 427.45 g/mol. Its…
Tetracycline
The broad-spectrum antibiotic tetracycline belongs to the tetracycline class, with a molecular formula of C22H24N2O8 and a molecular mass of…
K-ras Transgenic Mouse Model of Gastric Cancer
The K-ras transgenic mouse model is engineered to express mutant K-ras specifically in the gastric epithelium, typically under the control…
H/K-ATPase-IL-1β Transgenic Mouse Model of Gastric Cancer
The H/K-ATPase-IL-1β transgenic mouse model is engineered to specifically express human interleukin-1β (IL-1β) in the stomach mucosa under the control…
Gastrin Knockout (GAS-KO) Mouse Model of Gastric Cancer
Gastrin Knockout (GAS-KO) mice represent a significant model for investigating gastric cancer development through the complete absence of gastrin expression….
INS-GAS Mouse Model of Gastric Cancer
The INS-GAS mouse model is a valuable research tool for studying gastric cancer development, created by combining the human gastrin…
Esomeprazole
Esomeprazole is a proton pump inhibitor (PPI) that suppresses gastric acid production by blocking the H+/K+ ATPase enzyme in the…
Amoxicillin
Amoxicillin is a broad-spectrum penicillin antibiotic that works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs)….
Vonoprazan
Vonoprazan is a potassium-competitive acid blocker (P-CAB) that reversibly inhibits the H+/K+ ATPase enzyme in the stomach’s parietal cells. Unlike…
Omeprazole
Omeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production by blocking the H+/K+ ATPase enzyme in the…
Lansoprazole
Lansoprazole is a proton pump inhibitor (PPI) that effectively reduces stomach acid production by blocking the hydrogen/potassium adenosine triphosphatase (H+/K+…
Therapeutic Approaches for Helicobacter pylori Infection
Helicobacter pylori infects the stomach of humans. It is a common cause of peptic ulcers and gastric cancer. The treatment…